How do i get rid of this discusting wart on my knuckle?

You can pick up a good wart remover at Walgreen's or most other drug stores. Using one of these will not only remove the wart in just a couple of days, it will also kill the virus.
 
Cut a small circle of duct tape (same size as the wart). Place on wart and change daily.
 
You need to see a dermatologist. A wart is a type of virus in the skin. Over the counter treatments tend to treat a certain type of virus. It sounds like you need a prescription treatment.
 
My husband, my dad, and my brother all had warts..My brother went to the dr to have his removed. My husband and dad dug in theirs until they got the seed out..None have reappeared.
 
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