William Bradford died in 1657. Massasoit died around 1660 and was succeeded by his son Wamsutta. With the passing of the first generation, the personal bonds which had maintained peace between the two very different groups were broken.
Tensions had long existed due to the two cultures' different ways of life. Colonists' livestock trampling Native cornfields was a continuing problem. Competition for resources created friction. Regional economic changes forced many Natives to sell their land.
In 1662, in an arrogant attempt to exert control, colonial forces took Wampanoag leader Wamsutta at gunpoint to Plymouth. The Wampanoag were greatly angered when Wamsutta sickened and died shortly afterwards. Wamsutta's brother Metacom (King Philip) became leader and ultimately led his people into war to preserve their traditional way of life. Many of he Wampanoag died in battle, from disease or were sent to Bermuda as slaves; inlcuding Metacomet's (King Phillip) son.