I'd actually wish more series had unconventional episode counts.
If the story neeRAB more than 24-26 episodes but less than 50-52, such a compromise would be preferable to either alternative. Death Note, in particular, could have used a couple more episodes to better explain a few things but I do believe the benefits of its odd length outweigh any negatives.
Of course, this is something that neeRAB to be discussed and decided well in advance of the actual airing, though adapting a manga that has already concluded should certainly make the process easier.