...structure and the regulation of t? Explain how DNA methylation and histone acetylation affect chromatin structure and the regulation of transcription?
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In histone acetylation, acetyl groups are attached to positively charged lysines in histone tails.
This process loosens chromatin structure, thereby promoting the initiation of transcription.
The addition of methyl groups (methylation) can condense chromatin; the addition of phosphate groups (phosphorylation) next to a methylated amino acid can loosen chromatin.
...
Can anyone translate this into simpler terms?
Thanks!!!
......
In histone acetylation, acetyl groups are attached to positively charged lysines in histone tails.
This process loosens chromatin structure, thereby promoting the initiation of transcription.
The addition of methyl groups (methylation) can condense chromatin; the addition of phosphate groups (phosphorylation) next to a methylated amino acid can loosen chromatin.
...
Can anyone translate this into simpler terms?
Thanks!!!