There are different types of medications for reflux including antiaciRAB, H2 blockers and PPI's like Nexium.
The best approach to treat reflux entails taking medication along with lifestyle and diet changes.
There are many different PPI's on the market and you may have to try different ones until you find one that works for you. Aciphex worked very well for me but I eventually decided to discontinue it due to other undesirable side effects. Others swear by Prilosec, Zegerid or a nuraber of other PPI's that are out there.
Rose