a level biology questions HELP please?

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imported_rock_chick

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1/ explain how a change in the primary structure of a globular protein may result in a different three dimensional structure

and the other question is

2/ PrP molecules are found on the outside of the cell surface membranes of nerve cells. The precise function of PrP is still unknown but it is thought that its tertiary structure enables it to act as a receptor molecule..... explain how its tertiary structure might allow a protein molecule to act as a receptor molecule

much thanks
any help will do
xxx
 
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