It happens from time to time. Usually I play it one of two completely different ways, depending on the mood:
1) I'll say, pretending to hold back tears "Fine, I don't need you people anyway, I'm laughing, that's all that matters, really. SCREW YOU ALL. I DON'T NEED YOU!!!!"
2) "Okay, I guess that wasn't your cup of tea. Let's try this one..." and bust out my old trusty daddy longlegs joke.