With all my books (which I have to bring home every day) my backpack is usually around 25 pounds. The chiropractor gives some relief but I think this is a major factor in my back and neck pain, I can even feel it when I'm carrying the backpack it is the cause of my pain.
So is 25 pounds too...
For example, if you're empathetic you may donate a lot of money to starving children, but you could also be investing that money and getting more money for yourself.
You may be a manager and not fire someone who is inadequate for the job, because you know they won't get a job anywhere else...